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Cellosaurus HBL-6 (CVCL_4221)

[Text version]
Cell line name HBL-6
Synonyms HBL6; BHL-6
Accession CVCL_4221
Resource Identification Initiative To cite this cell line use: HBL-6 (RRID:CVCL_4221)
Comments Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11762.
Population: Caucasian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Transformant: NCBI_TaxID; 37296; Human herpesvirus 8 (HHV-8/KSHV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Disease Primary effusion lymphoma (NCIt: C6915)
Primary effusion lymphoma (ORDO: Orphanet_48686)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1079 ! BC-1
Sex of cell Male
Age at sampling 46Y
Category Cancer cell line
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=HBL-6
Publications

PubMed=8523568; DOI=10.1128/JVI.70.1.549-558.1996
Moore P.S., Gao S.-J., Dominguez G., Cesarman E., Lungu O., Knowles D.M., Garber R., Pellett P.E., McGeoch D.J., Chang Y.
Primary characterization of a herpesvirus agent associated with Kaposi's sarcomae.
J. Virol. 70:549-558(1996)

PubMed=8684008
Gaidano G., Cechova K., Chang Y., Moore P.S., Knowles D.M., Dalla-Favera R.
Establishment of AIDS-related lymphoma cell lines from lymphomatous effusions.
Leukemia 10:1237-1240(1996)

Patent=US5849564
Chang Y., Bohenzky R.A., Russo J.J., Edelman I.S., Moore P.S.
Polypeptides from Kaposi's sarcoma-associated herpesvirus, DNA encoding same and uses thereof.
Patent number US5849564, 15-Dec-1998

PubMed=9473233; DOI=10.1182/blood.V91.5.1671
Boshoff C., Gao S.-J., Healy L.E., Matthews S., Thomas A.J., Coignet L.J.A., Warnke R.A., Strauchen J.A., Matutes E., Kamel O.W., Moore P.S., Weiss R.A., Chang Y.
Establishing a KSHV+ cell line (BCP-1) from peripheral blood and characterizing its growth in Nod/SCID mice.
Blood 91:1671-1679(1998)

PubMed=9766492; DOI=10.1038/sj.leu.2401160
Drexler H.G., Uphoff C.C., Gaidano G., Carbone A.
Lymphoma cell lines: in vitro models for the study of HHV-8+ primary effusion lymphomas (body cavity-based lymphomas).
Leukemia 12:1507-1517(1998)

Patent=US5861500
Chang Y., Bohenzky R.A., Russo J.J., Edelman I.S., Moore P.S.
Kaposi's sarcoma-associated herpesvirus (KSHV) interleukin 6 (IL-6) and uses thereof.
Patent number US5861500, 19-Jan-1999

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=15028022; DOI=10.1111/j.1440-1827.2004.01612.x
Kamimura K., Hojo H., Abe M.
Characterization of expression of protein kinase C isozymes in human B-cell lymphoma: relationship between its expression and prognosis.
Pathol. Int. 54:224-230(2004)

Cross-references
Anatomy/cell type resources BTO; BTO:0002723
Encyclopedic resources Wikidata; Q54881439
Polymorphism and mutation databases Cosmic; 1515189
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number17