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Cellosaurus L-5178-Y-S (CVCL_4235)

Cell line name L-5178-Y-S
Synonyms L5178Y-S; L5178YS; L5178-S; LY-S
Accession CVCL_4235
Resource Identification Initiative To cite this cell line use: L-5178-Y-S (RRID:CVCL_4235)
Comments Characteristics: Compared to the parent cell line, this cell line is sensitive to X-rays.
Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
Cell type: T-cell; CL=CL_0000084.
Disease Mouse thymic lymphoma (NCIt: C134997)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Parent: CVCL_4234 (L-5178-Y-R)
Children:
CVCL_6665 (L5178Y TK+/- (clone 3.7.2C))
Sex of cell Female
Age at sampling 8M
Category Cancer cell line
Publications

PubMed=6883332
Beer J.Z., Budzicka E., Niepokojczycka E., Rosiek O., Szumiel I., Walicka M.
Loss of tumorigenicity with simultaneous changes in radiosensitivity and photosensitivity during in vitro growth of L5178Y murine lymphoma cells.
Cancer Res. 43:4736-4742(1983)

PubMed=3876312; DOI=10.1080/09553008514551671
Beer J.Z., Mencl J., Horng M.-F., Gregg E.C., Evans H.H.
Effects of low dose rate (0.003-0.025 Gy/h) chronic X-irradiation on radioresistant and radiosensitive L5178Y mouse lymphoma cells.
Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 48:609-619(1985)

PubMed=3012566; DOI=10.1073/pnas.83.12.4379
Evans H.H., Mencl J., Horng M.-F., Ricanati M., Sanchez C., Hozier J.C.
Locus specificity in the mutability of L5178Y mouse lymphoma cells: the role of multilocus lesions.
Proc. Natl. Acad. Sci. U.S.A. 83:4379-4383(1986)

Cross-references
Cell line collections (Providers) ATCC; CRL-1723
ECACC; 93050408
KCLB; 21723
RCB; RCB2636 - Discontinued
TKG; TKG 0576 - Discontinued
Cell line databases/resources CLO; CLO_0007194
CLO; CLO_0007198
CLDB; cl3137
Encyclopedic resources Wikidata; Q54900873
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number12