ID   PDVC 57B
AC   CVCL_4271
SY   PDVC57B; PDVC57b; PDVC57; PDV.C57; PDV C57
DR   CancerTools; 151630
DR   ECACC; 01022129
DR   Wikidata; Q54946871
DR   Ximbio; 151630
RX   PubMed=1855225;
RX   PubMed=1934268;
RX   PubMed=2185890;
RX   PubMed=2414007;
RX   PubMed=12807763;
CC   Transformant: ChEBI; CHEBI:59032; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
CC   Breed/subspecies: C57BL/10 LP.
DI   NCIt; C21810; Spindle-cell squamous cell carcinoma of the mouse skin
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_5858 ! PDV
SX   Sex unspecified
AG   <1D
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 13
//
RX   PubMed=1855225;
RA   Buchmann A., Ruggeri B., Klein-Szanto A.J.P., Balmain A.;
RT   "Progression of squamous carcinoma cells to spindle carcinomas of
RT   mouse skin is associated with an imbalance of H-ras alleles on
RT   chromosome 7.";
RL   Cancer Res. 51:4097-4101(1991).
//
RX   PubMed=1934268; DOI=10.1093/carcin/12.10.1875;
RA   Quintanilla M., Haddow S., Jonas D., Jaffe D., Bowden G.T.,
RA   Balmain A.;
RT   "Comparison of ras activation during epidermal carcinogenesis in vitro
RT   and in vivo.";
RL   Carcinogenesis 12:1875-1881(1991).
//
RX   PubMed=2185890; DOI=10.1016/0092-8674(90)90523-H;
RA   Bremner R., Balmain A.;
RT   "Genetic changes in skin tumor progression: correlation between
RT   presence of a mutant ras gene and loss of heterozygosity on mouse
RT   chromosome 7.";
RL   Cell 61:407-417(1990).
//
RX   PubMed=2414007;
RA   Fusenig N.E., Dzarlieva-Petrusevska R.T., Breitkreutz D.;
RT   "Phenotypic and cytogenetic characteristics of different stages during
RT   spontaneous transformation of mouse keratinocytes in vitro.";
RL   Carcinog. Compr. Surv. 9:293-326(1985).
//
RX   PubMed=12807763; DOI=10.1093/carcin/bgg067;
RA   Zoumpourlis V., Solakidi S., Papathoma A., Papaevangeliou D.;
RT   "Alterations in signal transduction pathways implicated in tumour
RT   progression during multistage mouse skin carcinogenesis.";
RL   Carcinogenesis 24:1159-1165(2003).
//