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Cellosaurus Dami (CVCL_4360)

[Text version]

Cell line name Dami
Synonyms DAMI
Accession CVCL_4360
Resource Identification Initiative To cite this cell line use: Dami (RRID:CVCL_4360)
Comments Problematic cell line: Contaminated. Shown to be a HEL derivative (PubMed=9166871; PubMed=9326259; PubMed=10508494; PubMed=12592342; PubMed=20143388). Originally thought to originate from the peripheral blood of a 57 year old male patient with megakaryoblastic leukemia.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00116.
Population: Caucasian.
Derived from sampling site: Peripheral blood.
Sequence variations Mutation; HGNC; 6192; JAK2; Simple; p.Val617Phe (c.1849G>T); ClinVar=VCV000014662; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Met133Lys (c.398T>A); Zygosity=Homozygous (from parent cell line).
Disease Erythroleukemia (NCIt: C7152)
Acute erythroid leukemia (ORDO: Orphanet_318)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0001 (HEL)
Sex of cell Male
Age at sampling 30Y
Category Cancer cell line
STR profile Source(s): ATCC; CCRID

Markers:
AmelogeninX (CCRID)
X,Y (ATCC)
CSF1PO10
D2S133818,19
D3S135815
D5S81811
D7S8207
D8S117913,15
D13S3179,11
D16S53911
D18S5112,16
D19S43311,13
D21S1129,31.2
FGA22,23
TH017
TPOX11
vWA14,17

Run an STR similarity search on this cell line
Web pages https://www.atcc.org/support/faqs/fd471/DAMI%20ATCC%20CRL9792-1071.aspx
http://iclac.org/wp-content/uploads/Cross-Contaminations_v10_distribution.xlsx
Publications

PubMed=3196874; DOI=10.1182/blood.V72.6.1968.1968
Greenberg S.M., Rosenthal D.S., Greeley T.A., Tantravahi R., Handin R.I.
Characterization of a new megakaryocytic cell line: the Dami cell.
Blood 72:1968-1977(1988)

Patent=US5128245
Greenberg S.M., Handin R.I.
Establishment, characterization and differentiation of a new megakaryocytic cell line, the Dami cells.
Patent number US5128245, 07-Jul-1992

PubMed=9166871; DOI=10.1182/blood.V89.11.4238
Handin R.I.
DAMI cell line.
Blood 89:4238-4238(1997)

PubMed=9326259; DOI=10.1182/blood.V90.7.2850
MacLeod R.A.F., Dirks W.G., Drexler H.G.
Early contamination of the Dami cell line by HEL.
Blood 90:2850-2851(1997)

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=11021758; DOI=10.1038/sj.leu.2401891
Majka M., Rozmyslowicz T., Honczarenko M., Ratajczak J., Wasik M.A., Gaulton G.N., Ratajczak M.Z.
Biological significance of the expression of HIV-related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines.
Leukemia 14:1821-1832(2000)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Cell line collections ATCC; CRL-9792 - Discontinued
KCB; KCB 200782YJ
Cell line databases/resources CCRID; 3131C0001000700068
Lonza; 1426
Ontologies BTO; BTO:0001550
Biological sample resources BioSample; SAMN03151657
Other Wikidata; Q54828561
Polymorphism and mutation databases Cosmic; 1191696
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number25