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Cellosaurus Dami (CVCL_4360)

Cell line name Dami
Synonyms DAMI
Accession CVCL_4360
Resource Identification Initiative To cite this cell line use: Dami (RRID:CVCL_4360)
Comments Problematic cell line: Contaminated. Shown to be a HEL derivative (PubMed=10508494; PubMed=12592342; PubMed=20143388). Originally thought to originate from the peripheral blood of a 57 year old male patient with megakaryoblastic leukemia.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00116.
Derived from sampling site: Peripheral blood.
Sequence variations Homozygous for JAK2 p.Val617Phe (c.1849G>T) (from parent cell line).
Disease Erythroleukemia (NCIt: C7152)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0001 (HEL)
Sex of cell Male
Age at sampling 30Y
Category Cancer cell line
STR profile Source(s): ATCC

Web pages https://www.atcc.org/support/faqs/fd471/DAMI%20ATCC%20CRL9792-1071.aspx

Greenberg S.M., Rosenthal D.S., Greeley T.A., Tantravahi R., Handin R.I.
Characterization of a new megakaryocytic cell line: the Dami cell.
Blood 72:1968-1977(1988)

Greenberg S.M., Handin R.I.
Establishment, characterization and differentiation of a new megakaryocytic cell line, the Dami cells.
Patent number US5128245, 07-Jul-1992

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=11021758; DOI=10.1038/sj.leu.2401891
Majka M., Rozmyslowicz T., Honczarenko M., Ratajczak J., Wasik M.A., Gaulton G.N., Ratajczak M.Z.
Biological significance of the expression of HIV-related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines.
Leukemia 14:1821-1832(2000)

PubMed=12592342; DOI=10.1038/sj.leu.2402799
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Leukemia 17:416-426(2003)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cell line collections ATCC; CRL-9792
Cell line databases/resources CCRID; 3131C0001000700068
Lonza; 1426
Ontologies BTO; BTO:0001550
Biological sample resources BioSample; SAMN03151657
Other Wikidata; Q54828561
Polymorphism and mutation databases Cosmic; 1191696