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Cellosaurus NR8383 (CVCL_4396)

[Text version]

Cell line name NR8383
Synonyms NR-8383; NR 8383; NR8383.1; AgC11x3A; Normal Rat, August 3, 1983
Accession CVCL_4396
Resource Identification Initiative To cite this cell line use: NR8383 (RRID:CVCL_4396)
Comments Group: Space-flown cell line (cellonaut).
Characteristics: Provides a homogenous source of highly responsive alveolar macarophages which can be used in vitro to study macrophage related activities (ATCC).
Anecdotal: Have been flown in space on the ISS in 2014-2015 to study growth and adaptation to microgravity (PubMed=28242876).
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Sprague-Dawley.
Category Spontaneously immortalized cell line
Web pages http://www.cellresource.cn/fdetail.aspx?id=538
http://www.cellresource.cn/fdetail.aspx?id=2776
Publications

PubMed=3497918; DOI=10.1007/BF02620974
Helmke R.J., Boyd R.L., German V.F., Mangos J.A.
From growth factor dependence to growth factor responsiveness: the genesis of an alveolar macrophage cell line.
In Vitro Cell. Dev. Biol. 23:567-574(1987)

PubMed=2914814; DOI=10.1007/BF02624409
Helmke R.J., German V.F., Mangos J.A.
A continuous alveolar macrophage cell line: comparisons with freshly derived alveolar macrophages.
In Vitro Cell. Dev. Biol. 25:44-48(1989)

PubMed=9738661; DOI=10.1002/jlb.64.3.345
Lane K.B., Egan B., Vick S., Abdolrasulnia R., Shepherd V.L.
Characterization of a rat alveolar macrophage cell line that expresses a functional mannose receptor.
J. Leukoc. Biol. 64:345-350(1998)

PubMed=28242876; DOI=10.1038/s41598-017-00119-6
Thiel C.S., de Zelicourt D., Tauber S., Adrian A., Franz M., Simmet D.M., Schoppmann K., Hauschild S., Krammer S., Christen M., Bradacs G., Paulsen K., Wolf S.A., Braun M., Hatton J., Kurtcuoglu V., Franke S., Tanner S., Cristoforetti S., Sick B., Hock B., Ullrich O.
Rapid adaptation to microgravity in mammalian macrophage cells.
Sci. Rep. 7:43-43(2017)

Cross-references
Cell line collections ATCC; CRL-2192
BCRC; 60423
KCB; KCB 2010189YJ
Cell line databases/resources CCRID; 3111C0001CCC000663
CCRID; 3131C0001000500009
Lonza; 1390
Ontologies BTO; BTO:0002907
CLO; CLO_0008193
Other Wikidata; Q54931021
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number15