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Cellosaurus MM466 (CVCL_4449)

[Text version]
Cell line name MM466
Synonyms MM 466
Accession CVCL_4449
Resource Identification Initiative To cite this cell line use: MM466 (RRID:CVCL_4449)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Omics: CNV analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): CBA

Markers:
AmelogeninX
CSF1PO10,11
D2S133817
D3S135815
D5S81811,12
D7S8209,10
D8S117910,12
D13S31711
D16S53912,13
D18S5112,19
D19S43314,15
D21S1128,29
FGA22,26
TH019,9.3
TPOX9
vWA15,17

Run an STR similarity search on this cell line
Publications

PubMed=9354451
Castellano M., Pollock P.M., Walters M.K., Sparrow L.E., Down L.M., Gabrielli B.G., Parsons P.G., Hayward N.K.
CDKN2A/p16 is inactivated in most melanoma cell lines.
Cancer Res. 57:4868-4875(1997)

PubMed=15048078; DOI=10.1038/sj.onc.1207563
Pavey S., Johansson P., Packer L., Taylor J., Stark M.S., Pollock P.M., Walker G.J., Boyle G.M., Harper U., Cozzi S.-J., Hansen K., Yudt L., Schmidt C., Hersey P., Ellem K.A.O., O'Rourke M.G.E., Parsons P.G., Meltzer P.S., Ringner M., Hayward N.K.
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Oncogene 23:4060-4067(2004)

PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152
Stark M.S., Hayward N.K.
Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.
Cancer Res. 67:2632-2642(2007)

PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x
Johansson P., Pavey S., Hayward N.K.
Confirmation of a BRAF mutation-associated gene expression signature in melanoma.
Pigment Cell Res. 20:216-221(2007)

Cross-references
Cell line collections (Providers) CBA; CBA-1353
ECACC; 12070507
Cell line databases/resources cancercelllines; CVCL_4449
DepMap; ACH-001971
Biological sample resources BioSample; SAMN07624431
Encyclopedic resources Wikidata; Q54906142
Gene expression databases GEO; GSM162936
GEO; GSM226721
Polymorphism and mutation databases Cosmic; 889024
Cosmic; 928714
Cosmic; 1303047
Progenetix; CVCL_4449
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number23