ID   4MBr-5
AC   CVCL_4492
SY   4MBR-5
DR   CLO; CLO_0001400
DR   ATCC; CCL-208
DR   IZSLER; BS CL 222
DR   Wikidata; Q54603515
RX   CelloPub=CLPUB00288;
RX   DOI=10.1007/978-94-011-3550-4_4;
RX   DOI=10.1016/B978-012361946-4/50009-0;
RX   PubMed=7065527;
RX   PubMed=28046048;
CC   Group: Non-human primate cell line.
CC   Characteristics: EGF dependent.
CC   Senescence: Senesces at 40 PDL (PubMed=7065527).
CC   Virology: Susceptible to infection by poliovirus type 1, type 2 and type 3 (PubMed=28046048).
CC   Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
CC   Cell type: Epithelial cell of bronchus; CL=CL_0002328.
OX   NCBI_TaxID=9544; ! Macaca mulatta (Rhesus macaque)
SX   Female
AG   2-3Y
CA   Finite cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 17
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RX   CelloPub=CLPUB00288;
RA   Caputo J.L., Hay R.J., Williams C.D.;
RT   "The isolation and properties of an epithelial cell strain from rhesus
RT   monkey bronchus.";
RL   In Vitro 15:222-223(1979).
//
RX   DOI=10.1007/978-94-011-3550-4_4;
RA   Hay R.J.;
RT   "Development, availability and characterization of ATCC human and
RT   animal cell lines.";
RL   (In) Animal cell culture and production of biologicals; Sasaki R., Ikura K. (eds.); pp.27-39; Springer; Dordrecht (1991).
//
RX   DOI=10.1016/B978-012361946-4/50009-0;
RA   Hay R.J.;
RT   "Animal cells in culture.";
RL   (In) Maintaining cultures for biotechnology and industry; Hunter-Cevera J.C., Belt A. (eds.); pp.161-187; Academic Press; San Diego (1996).
//
RX   PubMed=7065527; DOI=10.1164/arrd.1982.125.2.222;
RA   Hay R.J., Williams C.D., Macy M.L., Lavappa K.S.;
RT   "Cultured cell lines for research on pulmonary physiology available
RT   through the American Type Culture Collection.";
RL   Am. Rev. Respir. Dis. 125:222-232(1982).
//
RX   PubMed=28046048; DOI=10.1371/journal.pone.0169391;
RA   Dotti S., Lombardo T., Villa R., Cacciamali A., Zanotti C.,
RA   Andreani N.A., Cinotti S., Ferrari M.;
RT   "Transformation and tumorigenicity testing of simian cell lines and
RT   evaluation of poliovirus replication.";
RL   PLoS ONE 12:E0169391-E0169391(2017).
//