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Cellosaurus MCC1 [Human Merkel cell carcinoma] (CVCL_4558)

[Text version]
Cell line name MCC1 [Human Merkel cell carcinoma]
Synonyms MCC1TC; MCC1 TC
Accession CVCL_4558
Resource Identification Initiative To cite this cell line use: MCC1 [Human Merkel cell carcinoma] (RRID:CVCL_4558)
Comments Characteristics: Derived from a xenograft.
Doubling time: 6 days (PubMed=8244578).
Caution: Was briefly displayed in Cell Bank Australia under catalog number CBA-1335 but was never distributed.
Disease Merkel cell carcinoma (NCIt: C9231)
Cutaneous neuroendocrine carcinoma (ORDO: Orphanet_79140)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 63Y
Category Cancer cell line
Publications

PubMed=8244578; DOI=10.1002/ijc.2910550519
Leonard J.H., Bell J.R., Kearsley J.H.
Characterization of cell lines established from Merkel-cell ('small-cell') carcinoma of the skin.
Int. J. Cancer 55:803-810(1993)

PubMed=8026890; DOI=10.1002/ijc.2910580223
Thomson J.A.F., Leonard J.H., McGregor K., Sturm R.A., Parsons P.G.
A nonconsensus octamer-recognition sequence (TAATGARAT-motif) identifies a novel DNA binding protein in human Merkel cell carcinoma cell lines.
Int. J. Cancer 58:285-290(1994)

PubMed=11433400; DOI=10.1002/ijc.1352
Cook A.L., Pollock P.M., Welch J., Walsh M.D., Bowman R.V., Baumann K.C., Hayward N.K., Leonard J.H.
CDKN2A is not the principal target of deletions on the short arm of chromosome 9 in neuroendocrine (Merkel cell) carcinoma of the skin.
Int. J. Cancer 93:361-367(2001)

PubMed=12209986; DOI=10.1002/ijc.10554
Leonard J.H., Cook A.L., Van Gele M., Boyle G.M., Inglis K.J., Speleman F., Sturm R.A.
Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell carcinoma.
Int. J. Cancer 101:103-110(2002)

Cross-references
Encyclopedic resources Wikidata; Q54904249
Polymorphism and mutation databases Cosmic; 912927
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number11