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Cellosaurus CHL/IU (CVCL_4585)

[Text version]

Cell line name CHL/IU
Synonyms CHL-IU; CHL-CL-11; CHL-11
Accession CVCL_4585
Resource Identification Initiative To cite this cell line use: CHL/IU (RRID:CVCL_4585)
Comments Characteristics: Useful for screening chemical for ability to induce chromosomal aberrations (ATCC).
Doubling time: 15 hours (ATCC).
Derived from sampling site: Lung.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0212 (CHL)
Sex of cell Female
Age at sampling 1D
Category Spontaneously immortalized cell line

PubMed=9118971; DOI=10.1002/(SICI)1098-2280(1997)29:2<189::AID-EM10>3.0.CO;2-A
Galloway S.M., Sofuni T., Shelby M.D., Thilagar A., Kumaroo V., Kaur P., Gulati D., Putman D.L., Murli H., Marshall R., Tanaka N., Anderson B., Zeiger E., Ishidate M. Jr.
Multilaboratory comparison of in vitro tests for chromosome aberrations in CHO and CHL cells tested under the same protocols.
Environ. Mol. Mutagen. 29:189-207(1997)

PubMed=9393622; DOI=10.1016/S1383-5718(97)00114-9
Yamada T., Odawara K., Kishida F., Nakatsuka I., Yoshitake A.
Development of a novel CHL/IU cell line with an incorporated gpt shuttle vector for concurrent analysis of gene mutations and chromosome aberrations.
Mutat. Res. 393:295-306(1997)

PubMed=10320750; DOI=10.1016/S0027-5107(99)00077-9
Hu T., Miller C.M., Ridder G.M., Aardema M.J.
Characterization of p53 in Chinese hamster cell lines CHO-K1, CHO-WBL, and CHL: implications for genotoxicity testing.
Mutat. Res. 426:51-62(1999)

PubMed=27692294; DOI=10.1016/j.mrgentox.2016.08.001
Lorge E., Moore M.M., Clements J., O'Donovan M., Fellows M.D., Honma M., Kohara A., Galloway S., Armstrong M.J., Thybaud V., Gollapudi B., Aardema M.J., Tanir J.Y.
Standardized cell sources and recommendations for good cell culture practices in genotoxicity testing.
Mutat. Res. 809:1-15(2016)

Cell line collections ATCC; CRL-1935
Ontologies CLO; CLO_0002419
Other Wikidata; Q54812133
Entry history
Entry creation04-Apr-2012
Last entry update12-Jan-2021
Version number10