ID   CHL/IU
AC   CVCL_4585
SY   CHL-IU; CHL-CL-11; CHL-11
DR   CLO; CLO_0002419
DR   ATCC; CRL-1935
DR   Wikidata; Q54812133
RX   PubMed=9118971;
RX   PubMed=9393622;
RX   PubMed=10320750;
RX   PubMed=27692294;
CC   Characteristics: Useful for screening chemical for ability to induce chromosomal aberrations (ATCC=CRL-1935).
CC   Doubling time: 15 hours (ATCC=CRL-1935).
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0212 ! CHL
SX   Female
AG   1D
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 12
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RX   PubMed=9118971; DOI=10.1002/(SICI)1098-2280(1997)29:2<189::AID-EM10>3.0.CO;2-A;
RA   Galloway S.M., Sofuni T., Shelby M.D., Thilagar A., Kumaroo V.,
RA   Kaur P., Gulati D., Putman D.L., Murli H., Marshall R., Tanaka N.,
RA   Anderson B., Zeiger E., Ishidate M. Jr.;
RT   "Multilaboratory comparison of in vitro tests for chromosome
RT   aberrations in CHO and CHL cells tested under the same protocols.";
RL   Environ. Mol. Mutagen. 29:189-207(1997).
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RX   PubMed=9393622; DOI=10.1016/S1383-5718(97)00114-9;
RA   Yamada T., Odawara K., Kishida F., Nakatsuka I., Yoshitake A.;
RT   "Development of a novel CHL/IU cell line with an incorporated gpt
RT   shuttle vector for concurrent analysis of gene mutations and
RT   chromosome aberrations.";
RL   Mutat. Res. 393:295-306(1997).
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RX   PubMed=10320750; DOI=10.1016/S0027-5107(99)00077-9;
RA   Hu T., Miller C.M., Ridder G.M., Aardema M.J.;
RT   "Characterization of p53 in Chinese hamster cell lines CHO-K1,
RT   CHO-WBL, and CHL: implications for genotoxicity testing.";
RL   Mutat. Res. 426:51-62(1999).
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RX   PubMed=27692294; DOI=10.1016/j.mrgentox.2016.08.001;
RA   Lorge E., Moore M.M., Clements J., O'Donovan M., Fellows M.D., Honma M.,
RA   Kohara A., Galloway S., Armstrong M.J., Thybaud V., Gollapudi B.,
RA   Aardema M.J., Tanir J.Y.;
RT   "Standardized cell sources and recommendations for good cell culture
RT   practices in genotoxicity testing.";
RL   Mutat. Res. 809:1-15(2016).
//