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Cellosaurus UV24 (CVCL_4597)

[Text version]

Cell line name UV24
Synonyms UV-24; UV 24; 60-21
Accession CVCL_4597
Resource Identification Initiative To cite this cell line use: UV24 (RRID:CVCL_4597)
Comments Transformant: NCIt; C17231; Ultraviolet radiation.
Derived from sampling site: Ovary.
Sequence variations Mutation; UniProtKB; A0MQ57; Ercc3; Simple; p.Ser382Pro (c.1144T>C); Zygosity=Unspecified (PubMed=16143348).
Mutation; UniProtKB; A0MQ57; Ercc3; Simple; p.Gln739Ter (c.2215C>T); Zygosity=Unspecified (PubMed=16143348).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4386 (CHO-AA8)
CVCL_1S05 (GM10826)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line

PubMed=6943579; DOI=10.1073/pnas.78.6.3734
Thompson L.H., Busch D.B., Brookman K., Mooney C.L., Glaser D.A.
Genetic diversity of UV-sensitive DNA repair mutants of Chinese hamster ovary cells.
Proc. Natl. Acad. Sci. U.S.A. 78:3734-3737(1981)

Hoy C.A., Thompson L.H., Mooney C.L., Salazar E.P.
Defective DNA cross-link removal in Chinese hamster cell mutants hypersensitive to bifunctional alkylating agents.
Cancer Res. 45:1737-1743(1985)

PubMed=2687628; DOI=10.1093/mutage/4.5.349
Busch D.B., Greiner C., Lewis K., Ford R., Adair G.M., Thompson L.H.
Summary of complementation groups of UV-sensitive CHO cell mutants isolated by large-scale screening.
Mutagenesis 4:349-354(1989)

PubMed=8765433; DOI=10.1007/s002800050504
Andersson B.S., Sadeghi T., Siciliano M.J., Legerski R., Murray D.
Nucleotide excision repair genes as determinants of cellular sensitivity to cyclophosphamide analogs.
Cancer Chemother. Pharmacol. 38:406-416(1996)

PubMed=16143348; DOI=10.1016/j.mrfmmm.2005.07.013
Hall H., Gursky J., Nicodemou A., Rybanska I., Kimlickova E., Pirsel M.
Characterization of ERCC3 mutations in the Chinese hamster ovary 27-1, UV24 and MMC-2 cell lines.
Mutat. Res. 593:177-186(2006)

Cell line collections ATCC; CRL-1866
BCRC; 60175
Ontologies CLO; CLO_0009494
Other Wikidata; Q54992341
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number14