ID   UV24
AC   CVCL_4597
SY   UV-24; UV 24; 60-21
DR   CLO; CLO_0009494
DR   ATCC; CRL-1866
DR   BCRC; 60175
DR   Wikidata; Q54992341
RX   PubMed=2687628;
RX   PubMed=3919945;
RX   PubMed=6943579;
RX   PubMed=8765433;
RX   PubMed=16143348;
CC   Sequence variation: Mutation; UniProtKB; A0MQ57; Ercc3; Simple; p.Ser382Pro (c.1144T>C); Zygosity=Unspecified (PubMed=16143348).
CC   Sequence variation: Mutation; UniProtKB; A0MQ57; Ercc3; Simple; p.Gln739Ter (c.2215C>T); Zygosity=Unspecified (PubMed=16143348).
CC   Transformant: NCIt; C17231; Ultraviolet radiation.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_4386 ! CHO-AA8
SX   Female
AG   Adult
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 17
//
RX   PubMed=2687628; DOI=10.1093/mutage/4.5.349;
RA   Busch D.B., Greiner C., Lewis K., Ford R., Adair G.M., Thompson L.H.;
RT   "Summary of complementation groups of UV-sensitive CHO cell mutants
RT   isolated by large-scale screening.";
RL   Mutagenesis 4:349-354(1989).
//
RX   PubMed=3919945;
RA   Hoy C.A., Thompson L.H., Mooney C.L., Salazar E.P.;
RT   "Defective DNA cross-link removal in Chinese hamster cell mutants
RT   hypersensitive to bifunctional alkylating agents.";
RL   Cancer Res. 45:1737-1743(1985).
//
RX   PubMed=6943579; DOI=10.1073/pnas.78.6.3734;
RA   Thompson L.H., Busch D.B., Brookman K., Mooney C.L., Glaser D.A.;
RT   "Genetic diversity of UV-sensitive DNA repair mutants of Chinese
RT   hamster ovary cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 78:3734-3737(1981).
//
RX   PubMed=8765433; DOI=10.1007/s002800050504;
RA   Andersson B.S., Sadeghi T., Siciliano M.J., Legerski R.J., Murray D.;
RT   "Nucleotide excision repair genes as determinants of cellular
RT   sensitivity to cyclophosphamide analogs.";
RL   Cancer Chemother. Pharmacol. 38:406-416(1996).
//
RX   PubMed=16143348; DOI=10.1016/j.mrfmmm.2005.07.013;
RA   Hall H., Gursky J., Nicodemou A., Rybanska I., Kimlickova E.,
RA   Pirsel M.;
RT   "Characterization of ERCC3 mutations in the Chinese hamster ovary
RT   27-1, UV24 and MMC-2 cell lines.";
RL   Mutat. Res. 593:177-186(2006).
//