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Cellosaurus CHO-xrs-5 (CVCL_4601)

[Text version]

Cell line name CHO-xrs-5
Synonyms CHO-XRS5; CHO-xrs5; CHO Xrs5; XRS-5; Xrs-5; xrs-5; xrs 5; XrS5; xrs5
Accession CVCL_4601
Resource Identification Initiative To cite this cell line use: CHO-xrs-5 (RRID:CVCL_4601)
Comments Derived from sampling site: Ovary.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line

PubMed=6197643; DOI=10.1016/0167-8817(83)90026-3
Jeggo P.A., Kemp L.M.
X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation and cross-sensitivity to other DNA-damaging agents.
Mutat. Res. 112:313-327(1983)

PubMed=2564870; DOI=10.1080/09553008914550651
Denekamp J., Whitmore G.F., Jeggo P.A.
Biphasic survival curves for XRS radiosensitive cells: subpopulations or transient expression of repair competence?
Int. J. Radiat. Biol. 55:605-617(1989)

PubMed=2218721; DOI=10.1007/BF01232460
Wahls W.P., Moore P.D.
Relative frequencies of homologous recombination between plasmids introduced into DNA repair-deficient and other mammalian somatic cell lines.
Somat. Cell Mol. Genet. 16:321-329(1990)

PubMed=7603335; DOI=10.1093/mutage/10.2.91
Liu G., Lehnert S., Chow T.Y.-K.
Mammalian endo-exonuclease activity and its level in various radiation sensitive cell lines.
Mutagenesis 10:91-94(1995)

PubMed=9032253; DOI=10.1128/MCB.17.3.1264
Singleton B.K., Priestley A., Steingrimsdottir H., Gell D., Blunt T., Jackson S.P., Lehmann A.R., Jeggo P.A.
Molecular and biochemical characterization of xrs mutants defective in Ku80.
Mol. Cell. Biol. 17:1264-1273(1997)

PubMed=22923057; DOI=10.3892/or.2012.1982
Genet S.C., Maeda J., Fujisawa H., Yurkon C.R., Fujii Y., Romero A.M., Genik P.C., Fujimori A., Kitamura H., Kato T.A.
Comparison of cellular lethality in DNA repair-proficient or -deficient cell lines resulting from exposure to 70 MeV/n protons or 290 MeV/n carbon ions.
Oncol. Rep. 28:1591-1596(2012)

Cell line collections ATCC; CRL-2348
Ontologies CLO; CLO_0009691
Other Wikidata; Q54813131
Entry history
Entry creation04-Apr-2012
Last entry update12-Mar-2020
Version number7