ID   CHO-xrs-5
AC   CVCL_4601
SY   CHO-XRS5; CHO-xrs5; CHO Xrs5; XRS-5; Xrs-5; xrs-5; xrs 5; XrS5; xrs5
DR   CLO; CLO_0009691
DR   ATCC; CRL-2348
DR   Wikidata; Q54813131
RX   PubMed=2218721;
RX   PubMed=2564870;
RX   PubMed=6197643;
RX   PubMed=7603335;
RX   PubMed=9032253;
RX   PubMed=22923057;
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 10
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RX   PubMed=2218721; DOI=10.1007/BF01232460;
RA   Wahls W.P., Moore P.D.;
RT   "Relative frequencies of homologous recombination between plasmids
RT   introduced into DNA repair-deficient and other mammalian somatic cell
RT   lines.";
RL   Somat. Cell Mol. Genet. 16:321-329(1990).
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RX   PubMed=2564870; DOI=10.1080/09553008914550651;
RA   Denekamp J., Whitmore G.F., Jeggo P.A.;
RT   "Biphasic survival curves for XRS radiosensitive cells: subpopulations
RT   or transient expression of repair competence?";
RL   Int. J. Radiat. Biol. 55:605-617(1989).
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RX   PubMed=6197643; DOI=10.1016/0167-8817(83)90026-3;
RA   Jeggo P.A., Kemp L.M.;
RT   "X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation
RT   and cross-sensitivity to other DNA-damaging agents.";
RL   Mutat. Res. 112:313-327(1983).
//
RX   PubMed=7603335; DOI=10.1093/mutage/10.2.91;
RA   Liu G.-J., Lehnert S., Chow T.Y.-K.;
RT   "Mammalian endo-exonuclease activity and its level in various
RT   radiation sensitive cell lines.";
RL   Mutagenesis 10:91-94(1995).
//
RX   PubMed=9032253; DOI=10.1128/mcb.17.3.1264;
RA   Singleton B.K., Priestley A., Steingrimsdottir H., Gell D., Blunt T.,
RA   Jackson S.P., Lehmann A.R., Jeggo P.A.;
RT   "Molecular and biochemical characterization of xrs mutants defective
RT   in Ku80.";
RL   Mol. Cell. Biol. 17:1264-1273(1997).
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RX   PubMed=22923057; DOI=10.3892/or.2012.1982;
RA   Genet S.C., Maeda J., Fujisawa H., Yurkon C.R., Fujii Y., Romero A.M.,
RA   Genik P.C., Fujimori A., Kitamura H., Kato T.A.;
RT   "Comparison of cellular lethality in DNA repair-proficient or
RT   -deficient cell lines resulting from exposure to 70 MeV/n protons or
RT   290 MeV/n carbon ions.";
RL   Oncol. Rep. 28:1591-1596(2012).
//