Cellosaurus PCM6 (CVCL_4666)

Cell line name PCM6
Accession CVCL_4666
Resource Identification Initiative To cite this cell line use: PCM6 (RRID:CVCL_4666)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Characteristics: Produces IgG lambda.
Characteristics: IL6 dependent.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Disease Plasma cell myeloma (NCIt: C3242)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): RCB

Markers:
AmelogeninX
CSF1PO12
D13S31711,12
D16S5399
D5S81810
D7S82011,12
TH017,9
TPOX10,11
vWA16,18
Publications

PubMed=8112425
Takahira H., Kozuru M., Hirata J., Obama K., Uike N., Iguchi H., Miyamura T., Yamashita S., Kono A., Umemura T.
Establishment of a human myeloma cell line with growth-promoting activity for bone marrow-derived fibroblastoid colony-forming cells.
Exp. Hematol. 22:261-266(1994)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Drexler H.G., Matsuo Y.
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

Cross-references
Cell line collections RCB; RCB1460
Cell line databases/resources CCLE; PCM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Ontologies CLO; CLO_0051009
Biological sample resources BioSample; SAMN03472144
Gene expression databases GEO; GSM887507
GEO; GSM888589