Cellosaurus PK-8 (CVCL_4718)

Cell line name PK-8
Synonyms PK8
Accession CVCL_4718
Resource Identification Initiative To cite this cell line use: PK-8 (RRID:CVCL_4718)
Comments Doubling time: 56 hours (PubMed=3547771).
Omics: Deep RNAseq analysis.
Omics: Metabolome analysis.
Omics: SNP array analysis.
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Derived from metastatic site: Liver.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
STR profile Source(s): PubMed=25877200; RCB; TKG

Markers:
AmelogeninX
CSF1PO10,12
D13S31711
D16S5399,10
D18S5113
D21S1131
D3S135816
D5S81813
D7S8209,12
D8S117913,15
FGA23
Penta D9
Penta E13,15
TH017
TPOX8,11
vWA16
Publications

PubMed=3547771; DOI=10.1620/tjem.150.231
Kobari M., Hisano H., Matsuno S., Sato T., Kan M., Tachibana T.
Establishment of six human pancreatic cancer cell lines and their sensitivities to anti-tumor drugs.
Tohoku J. Exp. Med. 150:231-248(1986)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=26216984; DOI=10.1073/pnas.1501605112
Daemen A., Peterson D., Sahu N., McCord R., Du X., Liu B., Kowanetz K., Hong R., Moffat J., Gao M., Boudreau A., Mroue R., Corson L., O'Brien T., Qing J., Sampath D., Merchant M., Yauch R., Manning G., Settleman J., Hatzivassiliou G., Evangelista M.
Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors.
Proc. Natl. Acad. Sci. U.S.A. 112:E4410-E4417(2015)

Cross-references
Cell line collections RCB; RCB2700
TKG; TKG 0383
Ontologies BTO; BTO:0004855
CLO; CLO_0050112
EFO; EFO_0006737
Biological sample resources BioSample; SAMN03472951
Polymorphism and mutation databases Cosmic; 707254
Cosmic; 1066177
Cosmic; 1644298