Cellosaurus cell line MX-1 (CVCL_4774)

• Mutation; HGNC; 11998; TP53; Simple; p.Gln52Valfs*3 (c.154_158delCAATG); Zygosity=Unspecified (PubMed=29045385).
  

PubMed=10969801
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Modeling precision treatment of breast cancer.
Genome Biol. 14:R110.1-R110.14(2013)

PubMed=25960936; DOI=10.4161/21624011.2014.954893
Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.
A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.
OncoImmunology 3:e954893.1-e954893.12(2014)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=29045385; DOI=10.1038/nature24006
Kategaya L., Di Lello P., Rouge L., Pastor R., Clark K.R., Drummond J., Kleinheinz T., Lin E., Upton J.-P., Prakash S., Heideker J., McCleland M.L., Ritorto M.S., Alessi D.R., Trost M., Bainbridge T.W., Kwok M.C.M., Ma T.P., Stiffler Z., Brasher B., Tang Y.-Y., Jaishankar P., Hearn B.R., Renslo A.R., Arkin M.R., Cohen F., Yu K.-B., Peale F.V., Gnad F., Chang M.T., Klijn C., Blackwood E., Martin S.E., Forrest W.F., Ernst J.A., Ndubaku C., Wang X.-J., Beresini M.H., Tsui V., Schwerdtfeger C., Blake R.A., Murray J., Maurer T., Wertz I.E.
USP7 small-molecule inhibitors interfere with ubiquitin binding.
Nature 550:534-538(2017)