Due to scheduled maintenance work, this service will not be available from Tuesday August 23rd 06:00 pm until Wednesday August 24th 08:00 am
CEST. Apologies for the inconvenience.
Cellosaurus LNCaP-AI (CVCL_4791)
[Text version]
| Cell line name |
LNCaP-AI
|
|---|
| Synonyms |
LNCAPAI; LNCaP-Androgen-Independent
|
|---|
| Accession |
CVCL_4791
|
|---|
| Resource Identification Initiative |
To cite this cell line use: LNCaP-AI (RRID:CVCL_4791) |
|---|
| Comments |
Population: Caucasian.
Omics: Transcriptome analysis.
|
|---|
| Sequence variations |
- Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
- Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
|
|---|
| Disease |
Prostate carcinoma (NCIt: C4863)
Derived from metastatic site: Left supraclavicular lymph node.
|
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606)
|
|---|
| Hierarchy |
Parent: CVCL_1379 (LNCaP clone FGC)
|
|---|
| Sex of cell |
Male
|
|---|
| Age at sampling |
50Y
|
|---|
| Category |
Cancer cell line
|
|---|
| Publications | PubMed=10537131; DOI=10.1210/endo.140.11.7086
Lu S., Tsai S.Y., Tsai M.-J.
Molecular mechanisms of androgen-independent growth of human prostate cancer LNCaP-AI cells.
Endocrinology 140:5054-5059(1999) |
|---|
| Cross-references |
|---|
| Encyclopedic resources |
Wikidata; Q54902831
|
|---|
| Gene expression databases |
GEO; GSM1374623
|
|---|
| Entry history |
|---|
| Entry creation | 04-Apr-2012 |
|---|
| Last entry update | 23-Jun-2022 |
|---|
| Version number | 18 |
|---|