Cellosaurus Sq-1 (CVCL_4900)

Cell line name Sq-1
Synonyms SQ-1; SQ1
Accession CVCL_4900
Resource Identification Initiative To cite this cell line use: Sq-1 (RRID:CVCL_4900)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Squamous cell lung carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): RCB; TKG

Markers:
AmelogeninX,Y
CSF1PO11,13
D13S3178
D16S5399,12
D5S81812,13
D7S8208,13
TH017
TPOX8,11
vWA19
Publications

PubMed=14581340
Yokoi S., Yasui K., Iizasa T., Imoto I., Fujisawa T., Inazawa J.
TERC identified as a probable target within the 3q26 amplicon that is detected frequently in non-small cell lung cancers.
Clin. Cancer Res. 9:4705-4713(2003)

PubMed=15746151; DOI=10.1093/hmg/ddi092
Izumi H., Inoue J., Yokoi S., Hosoda H., Shibata T., Sunamori M., Hirohashi S., Inazawa J., Imoto I.
Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers.
Hum. Mol. Genet. 14:997-1007(2005)

PubMed=19472407; DOI=10.1002/humu.21028
Blanco R., Iwakawa R., Tang M., Kohno T., Angulo B., Pio R., Montuenga L.M., Minna J.D., Yokota J., Sanchez-Cespedes M.
A gene-alteration profile of human lung cancer cell lines.
Hum. Mutat. 30:1199-1206(2009)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

Cross-references
Cell line collections RCB; RCB1905
TKG; TKG 0301
Cell line databases/resources CCLE; SQ1_LUNG
CGH-DB; 192-1
CGH-DB; 9181-4
Ontologies CLO; CLO_0050049
Biological sample resources BioSample; SAMN03472088
Gene expression databases GEO; GSM887647
GEO; GSM888739
Polymorphism and mutation databases Cosmic; 889087
Cosmic; 946075
Cosmic; 1048222
Cosmic; 1066172
Cosmic; 1219090
Cosmic; 1239913
Cosmic; 2060523