Cellosaurus SR DU-145 (CVCL_4901)

Cell line name SR DU-145
Synonyms SR DU 145; SR DU145
Accession CVCL_4901
Resource Identification Initiative To cite this cell line use: SR DU-145 (RRID:CVCL_4901)
Comments Selected for resistance to: ChEBI; CHEBI:45906; Suramin.
Sequence variation: Homozygous for CDKN2A p.Asp84Tyr (from parent cell line).
Sequence variation: Homozygous for RB1 p.Lys715Ter (from parent cell line).
Sequence variation: Homozygous for STK11 p.Lys178fs*86 (from parent cell line).
Sequence variation: Heterozygous for TP53 p.Val274Phe (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Derived from metastatic site: Brain.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0105 (DU145)
Sex of cell Male
Category Cancer cell line
Web pages http://capcelllines.ca/details.asp?id=74

PubMed=9923549; DOI=10.1007/s002800050884
Church D., Zhang Y., Rago R., Wilding G.
Efficacy of suramin against human prostate carcinoma DU145 xenografts in nude mice.
Cancer Chemother. Pharmacol. 43:198-204(1999)