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Cellosaurus SR DU-145 (CVCL_4901)

[Text version]

Cell line name SR DU-145
Synonyms SR DU 145; SR DU145
Accession CVCL_4901
Resource Identification Initiative To cite this cell line use: SR DU-145 (RRID:CVCL_4901)
Comments Selected for resistance to: ChEBI; CHEBI:45906; Suramin.
Sequence variations Homozygous for CDKN2A p.Asp84Tyr (c.250G>T) (from parent cell line).
Homozygous for RB1 p.Lys715Ter (c.2143A>T) (from parent cell line).
Homozygous for STK11 p.Lys178fs*86 (c.532_536delAAGCC) (from parent cell line).
Heterozygous for TP53 p.Pro223Leu (c.668C>T) and p.Val274Phe (c.820G>T) (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Derived from metastatic site: Brain.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0105 (DU145)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line

PubMed=9923549; DOI=10.1007/s002800050884
Church D., Zhang Y., Rago R., Wilding G.
Efficacy of suramin against human prostate carcinoma DU145 xenografts in nude mice.
Cancer Chemother. Pharmacol. 43:198-204(1999)

Other Wikidata; Q54955623
Entry history
Entry creation04-Apr-2012
Last entry updated25-Feb-2019
Version number13