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Cellosaurus LNCaP-CL1-GFP (CVCL_4924)

[Text version]
Cell line name LNCaP-CL1-GFP
Synonyms CL1-GFP
Accession CVCL_4924
Resource Identification Initiative To cite this cell line use: LNCaP-CL1-GFP (RRID:CVCL_4924)
Comments Population: Caucasian.
Characteristics: Androgen-independent. Has highly locally invasive and metastatic properties.
Transfected with: UniProtKB; P42212; GFP.
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3872 (LNCaP-CL1)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=10992426; DOI=10.1016/S0022-5347(05)67210-2
Patel B.J., Pantuck A.J., Zisman A., Tsui K.-H., Paik S.H., Caliliw R., Sheriff S., Wu L., deKernion J.B., Tso C.-L., Belldegrun A.S.
CL1-GFP: an androgen independent metastatic tumor model for prostate cancer.
J. Urol. 164:1420-1425(2000)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4924
Encyclopedic resources Wikidata; Q54902833
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number20