Cellosaurus logo
expasy logo

Cellosaurus CUTLL1 (CVCL_4966)

[Text version]
Cell line name CUTLL1
Synonyms CUTLL-1; Columbia University T-cell Lymphoblastic Lymphoma 1
Accession CVCL_4966
Resource Identification Initiative To cite this cell line use: CUTLL1 (RRID:CVCL_4966)
Comments Omics: Transcriptome analysis by microarray.
Misspelling: CUTTL-1; Note=Occasionally.
Misspelling: CUTTL1; Cosmic=1224376.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Gene fusion; HGNC; 7881; NOTCH1 + HGNC; 12155; TRB; Name(s)=TRB-NOTCH1, TCRB-NOTCH1 (PubMed=16688224).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (PubMed=16688224).
Disease Childhood T lymphoblastic lymphoma (NCIt: C7210)
T-cell non-Hodgkin lymphoma (ORDO: Orphanet_171918)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
STR profile Source(s): Millipore

Markers:
AmelogeninX,Y
CSF1PO10,11,13
D3S135814,15,17
D5S8189,10,12
D7S8208,10
D8S117911,12,13
D13S3178,10,11,12
D16S5399,10,11
D18S5113,14,16,20,21
D21S1129,31.2,32.2,33.2,34.2
FGA19,21,22,24
Penta D10,11,12,12.4,14
Penta E8,10,12
TH016,7,9.3
TPOX8,10
vWA16,18,19

Run an STR similarity search on this cell line
Publications

PubMed=16688224; DOI=10.1038/sj.leu.2404258
Palomero T., Barnes K.C., Real P.J., Glade Bender J.L., Sulis M.L., Murty V.V.V.S., Colovai A.I., Balbin M., Ferrando A.A.
CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to gamma-secretase inhibitors.
Leukemia 20:1279-1287(2006)

Cross-references
Cell line collections (Providers) ABM; T8008
Millipore; SCC286
Cell line databases/resources cancercelllines; CVCL_4966
Chemistry resources ChEMBL-Cells; CHEMBL4651374
PubChem_Cell_line; CVCL_4966
Encyclopedic resources Wikidata; Q54814867
Polymorphism and mutation databases Cosmic; 1224376
Cosmic; 1641388
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number18