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Cellosaurus MHCC97-L (CVCL_4973)

Cell line name MHCC97-L
Synonyms MHCC 97-L; MHCC97L
Accession CVCL_4973
Resource Identification Initiative To cite this cell line use: MHCC97-L (RRID:CVCL_4973)
Comments Population: Chinese.
Characteristics: Low metastatic potential.
Karyotypic information: Has lost chromosome Y.
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4971 (MHCC97)
Sex of cell Male
Age at sampling 39Y
Category Cancer cell line
Publications

PubMed=11819844; DOI=10.3748/wjg.v7.i5.630
Li Y., Tang Z.-Y., Ye S.-L., Liu Y.-K., Chen J., Xue Q., Chen J., Gao D.-M., Bao W.-H.
Establishment of cell clones with different metastatic potential from the metastatic hepatocellular carcinoma cell line MHCC97.
World J. Gastroenterol. 7:630-636(2001)

PubMed=15048980; DOI=10.1002/pmic.200300653
Ding S.-J., Li Y., Shao X.-X., Zhou H., Zeng R., Tang Z.-Y., Xia Q.-C.
Proteome analysis of hepatocellular carcinoma cell strains, MHCC97-H and MHCC97-L, with different metastasis potentials.
Proteomics 4:982-994(2004)

PubMed=15146329; DOI=10.1007/s00432-004-0564-9
Li Y., Tian B., Yang J., Zhao L., Wu X., Ye S.-L., Liu Y.-K., Tang Z.-Y.
Stepwise metastatic human hepatocellular carcinoma cell model system with multiple metastatic potentials established through consecutive in vivo selection and studies on metastatic characteristics.
J. Cancer Res. Clin. Oncol. 130:460-468(2004)

PubMed=23505090; DOI=10.1002/hep.26402
Wang K., Lim H.Y., Shi S., Lee J., Deng S.-B., Xie T., Zhu Z., Wang Y.-L., Pocalyko D., Yang W.J., Rejto P.A., Mao M., Park C.-K., Xu J.-C.
Genomic landscape of copy number aberrations enables the identification of oncogenic drivers in hepatocellular carcinoma.
Hepatology 58:706-717(2013)

PubMed=32884988; DOI=10.1016/j.gendis.2019.12.008
Lin Y.-L., Li Y.
Study on the hepatocellular carcinoma model with metastasis.
Genes Dis. 7:336-350(2020)

Cross-references
Anatomy/cell type resources BTO; BTO:0004170
Encyclopedic resources Wikidata; Q54905534
Gene expression databases GEO; GSM501783
GEO; GSM936772
GEO; GSM1374676
Polymorphism and mutation databases Cosmic; 2773183
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number16