Cellosaurus CH1 [Human ovarian carcinoma] (CVCL_4992)

Cell line name CH1 [Human ovarian carcinoma]
Accession CVCL_4992
Resource Identification Initiative To cite this cell line use: CH1 [Human ovarian carcinoma] (RRID:CVCL_4992)
Comments Problematic cell line: Contaminated. Shown to be a PA-1 derivative (PubMed=22710073).
Doubling time: 17 hours (PubMed=2653399).
Omics: Transcriptome analysis.
Disease Ovarian mixed germ cell tumor (NCIt: C8814)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0479 (PA-1)
Children: CVCL_X012 (CH1-cisR); CVCL_Y426 (CH1:RD1694)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): PubMed=11416159

Markers:
AmelogeninX
D21S1129,31.2
D8S117914,15
FGA24
TH017,9
vWA15,17
Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations-v8_0.pdf
Publications

PubMed=2653399; DOI=10.1038/bjc.1989.108
Hills C.A., Kelland L.R., Abel G., Siracky J., Wilson A.P., Harrap K.R.
Biological properties of ten human ovarian carcinoma cell lines: calibration in vitro against four platinum complexes.
Br. J. Cancer 59:527-534(1989)

PubMed=1892748; DOI=10.1038/bjc.1991.279
Mistry P., Kelland L.R., Abel G., Sidhar S., Harrap K.R.
The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines.
Br. J. Cancer 64:215-220(1991)

PubMed=1423261
Mistry P., Kelland L.R., Loh S.Y., Abel G., Murrer B.A., Harrap K.R.
Comparison of cellular accumulation and cytotoxicity of cisplatin with that of tetraplatin and amminedibutyratodichloro(cyclohexylamine)platinum(IV) (JM221) in human ovarian carcinoma cell lines.
Cancer Res. 52:6188-6193(1992)

PubMed=1617660
Kelland L.R., Mistry P., Abel G., Loh S.Y., O'Neill C.F., Murrer B.A., Harrap K.R.
Mechanism-related circumvention of acquired cis-diamminedichloroplatinum(II) resistance using two pairs of human ovarian carcinoma cell lines by ammine/amine platinum(IV) dicarboxylates.
Cancer Res. 52:3857-3864(1992)

PubMed=15677628; DOI=10.1093/carcin/bgi032
Gorringe K.L., Chin S.-F., Pharoah P., Staines J.M., Oliveira C., Edwards P.A.W., Caldas C.
Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer.
Carcinogenesis 26:923-930(2005)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017
Korch C., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K., Lessey B.A., Jordan V.C., Bradford A.P.
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

Cross-references
Cell line databases/resources IGRhCellID; CH1
Biological sample resources BioSample; SAMN03151886
Chemistry resources ChEMBL-Cells; CHEMBL3307620
ChEMBL-Targets; CHEMBL614455
Gene expression databases GEO; GSM459735
GEO; GSM851914