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Cellosaurus PXN/94 (CVCL_4994)

Cell line name PXN/94
Synonyms PXN-94; PXN 94; PXN94; PxN94
Accession CVCL_4994
Resource Identification Initiative To cite this cell line use: PXN/94 (RRID:CVCL_4994)
Comments Characteristics: Established from a xenograft established in female nude mice (PubMed=2653399).
Doubling time: 23 hours (PubMed=2653399).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Disease Ovarian carcinoma (NCIt: C4908)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2653399; DOI=10.1038/bjc.1989.108
Hills C.A., Kelland L.R., Abel G., Siracky J., Wilson A.P., Harrap K.R.
Biological properties of ten human ovarian carcinoma cell lines: calibration in vitro against four platinum complexes.
Br. J. Cancer 59:527-534(1989)

PubMed=1892748; DOI=10.1038/bjc.1991.279
Mistry P., Kelland L.R., Abel G., Sidhar S., Harrap K.R.
The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines.
Br. J. Cancer 64:215-220(1991)

PubMed=1423261
Mistry P., Kelland L.R., Loh S.Y., Abel G., Murrer B.A., Harrap K.R.
Comparison of cellular accumulation and cytotoxicity of cisplatin with that of tetraplatin and amminedibutyratodichloro(cyclohexylamine)platinum(IV) (JM221) in human ovarian carcinoma cell lines.
Cancer Res. 52:6188-6193(1992)

PubMed=15677628; DOI=10.1093/carcin/bgi032
Gorringe K.L., Chin S.-F., Pharoah P.D.P., Staines J.M., Oliveira C., Edwards P.A.W., Caldas C.
Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer.
Carcinogenesis 26:923-930(2005)

Cross-references
Encyclopedic resources Wikidata; Q54948747
Polymorphism and mutation databases Cosmic; 688108
Cosmic; 1609540
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number10