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Cellosaurus HX/62 (CVCL_4995)

[Text version]
Cell line name HX/62
Synonyms HX-62; HX 62; HX62; Hx62
Accession CVCL_4995
Resource Identification Initiative To cite this cell line use: HX/62 (RRID:CVCL_4995)
Comments Population: Caucasian.
Characteristics: Established from a xenograft established in female nude mice (PubMed=2653399).
Doubling time: 32 hours (PubMed=2653399).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_0297 (HEY)CVCL_Y036 (Hx62-26)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2653399; DOI=10.1038/bjc.1989.108
Hills C.A., Kelland L.R., Abel G., Siracky J., Wilson A.P., Harrap K.R.
Biological properties of ten human ovarian carcinoma cell lines: calibration in vitro against four platinum complexes.
Br. J. Cancer 59:527-534(1989)

PubMed=1892748; DOI=10.1038/bjc.1991.279
Mistry P., Kelland L.R., Abel G., Sidhar S., Harrap K.R.
The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines.
Br. J. Cancer 64:215-220(1991)

PubMed=1423261
Mistry P., Kelland L.R., Loh S.Y., Abel G., Murrer B.A., Harrap K.R.
Comparison of cellular accumulation and cytotoxicity of cisplatin with that of tetraplatin and amminedibutyratodichloro(cyclohexylamine)platinum(IV) (JM221) in human ovarian carcinoma cell lines.
Cancer Res. 52:6188-6193(1992)

PubMed=15677628; DOI=10.1093/carcin/bgi032
Gorringe K.L., Chin S.-F., Pharoah P.D.P., Staines J.M., Oliveira C., Edwards P.A.W., Caldas C.
Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer.
Carcinogenesis 26:923-930(2005)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4995
Chemistry resources ChEMBL-Cells; CHEMBL3308618
ChEMBL-Targets; CHEMBL614686
PubChem_Cell_line; CVCL_4995
Encyclopedic resources Wikidata; Q54896958
Gene expression databases GEO; GSM313712
Polymorphism and mutation databases Cosmic; 1609539
Progenetix; CVCL_4995
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number18