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Cellosaurus MCF-7/CG-4 (CVCL_4D03)

[Text version]
Cell line name MCF-7/CG-4
Synonyms CG-4
Accession CVCL_4D03
Resource Identification Initiative To cite this cell line use: MCF-7/CG-4 (RRID:CVCL_4D03)
Comments Population: Caucasian.
Characteristics: Estrogen supersensitive (PubMed=6575841).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Publications

PubMed=6575841; DOI=10.1007/BF01806231
Natoli C., Sica G., Natoli V., Serra A., Iacobelli S.
Two new estrogen-supersensitive variants of the MCF-7 human breast cancer cell line.
Breast Cancer Res. Treat. 3:23-32(1983)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4D03
Encyclopedic resources Wikidata; Q54904359
Entry history
Entry creation22-Sep-2015
Last entry update05-Oct-2023
Version number14