ID   MCF-7/CG-4
AC   CVCL_4D03
SY   CG-4
DR   cancercelllines; CVCL_4D03
DR   Wikidata; Q54904359
RX   PubMed=6575841;
CC   Population: Caucasian.
CC   Characteristics: Estrogen supersensitive (PubMed=6575841).
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 22-09-15; Last updated: 05-10-23; Version: 14
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RX   PubMed=6575841; DOI=10.1007/BF01806231;
RA   Natoli C., Sica G., Natoli V., Serra A., Iacobelli S.;
RT   "Two new estrogen-supersensitive variants of the MCF-7 human breast
RT   cancer cell line.";
RL   Breast Cancer Res. Treat. 3:23-32(1983).
//