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Cellosaurus MP41 (CVCL_4D12)

[Text version]
Cell line name MP41
Accession CVCL_4D12
Resource Identification Initiative To cite this cell line use: MP41 (RRID:CVCL_4D12)
Comments Characteristics: Established from a patient-derived xenograft.
Doubling time: 41 hours (PubMed=24994677).
Omics: SNP array analysis.
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.
Sequence variations
  • Mutation; HGNC; 4379; GNA11; Simple; p.Gln209Leu (c.626A>T); ClinVar=VCV000376002; Zygosity=Unspecified (PubMed=24994677).
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 49Y
Category Cancer cell line
STR profile Source(s): ATCC; PubMed=24994677

Markers:
AmelogeninX
CSF1PO9,10
D5S81810,13
D7S8208.3,9,9.3,10,10.1,11 (ATCC)
9,10 (PubMed=24994677)
D13S31711,14
D16S53913
D21S1130.2,31.2
TH016,7
TPOX8,11
vWA15,18

Run an STR similarity search on this cell line
Publications

PubMed=24994677; DOI=10.1016/j.molonc.2014.06.004
Amirouchene-Angelozzi N., Nemati F., Gentien D., Nicolas A., Dumont A., Carita G., Camonis J., Desjardins L., Cassoux N., Piperno-Neumann S., Mariani P., Sastre X., Decaudin D., Roman-Roman S.
Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target.
Mol. Oncol. 8:1508-1520(2014)

Cross-references
Cell line collections (Providers) ATCC; CRL-3297
Cell line databases/resources cancercelllines; CVCL_4D12
Chemistry resources ChEMBL-Cells; CHEMBL4879544
Encyclopedic resources Wikidata; Q54906429
Entry history
Entry creation22-Sep-2015
Last entry update05-Oct-2023
Version number10