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Cellosaurus MP65 (CVCL_4D14)

[Text version]
Cell line name MP65
Accession CVCL_4D14
Resource Identification Initiative To cite this cell line use: MP65 (RRID:CVCL_4D14)
Comments Doubling time: 120 hours (PubMed=24994677).
Omics: SNP array analysis.
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.
Sequence variations
  • Mutation; HGNC; 950; BAP1; Simple; p.Leu573Trpfs*3 (c.1717delC); ClinVar=VCV000221278; Zygosity=Unspecified (PubMed=24994677).
  • Mutation; HGNC; 4379; GNA11; Simple; p.Gln209Leu (c.626A>T); ClinVar=VCV000376002; Zygosity=Unspecified (PubMed=24994677).
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): ATCC; PubMed=24994677

Markers:
AmelogeninX
CSF1PO10
D5S81812
D7S8208,11
D13S3178 (ATCC)
8,13 (PubMed=24994677)
D16S53911
D21S1130,30.2
TH017,9.3
TPOX8,12
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=24994677; DOI=10.1016/j.molonc.2014.06.004
Amirouchene-Angelozzi N., Nemati F., Gentien D., Nicolas A., Dumont A., Carita G., Camonis J., Desjardins L., Cassoux N., Piperno-Neumann S., Mariani P., Sastre X., Decaudin D., Roman-Roman S.
Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target.
Mol. Oncol. 8:1508-1520(2014)

Cross-references
Cell line collections (Providers) ATCC; CRL-3299
Cell line databases/resources cancercelllines; CVCL_4D14
Encyclopedic resources Wikidata; Q54906431
Entry history
Entry creation22-Sep-2015
Last entry update05-Oct-2023
Version number10