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Cellosaurus C-378 (CVCL_4J79)

[Text version]

Cell line name C-378
Synonyms C378
Accession CVCL_4J79
Resource Identification Initiative To cite this cell line use: C-378 (RRID:CVCL_4J79)
Comments Problematic cell line: Probably contaminated. The STR profile is identical to that of the RD-ES cell line. Originally thought to originate from a giant cell tumor excised in 1986 from tumor tissue of a 33 year old female patient.
Population: Caucasian.
Derived from sampling site: Bone; humerus.
Sequence variations Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Gene fusion; HGNC; 3508; EWSR1 + HGNC; 3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1; Note=Type 2 fusion (Ex7/Ex5) (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (from parent cell line).
Disease Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2169 (RD-ES)
Sex of cell Male
Age at sampling 19Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX,Y
CSF1PO11
D5S81811
D7S82010
D13S31711
D16S53911
TH017
TPOX9,11
vWA17

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Cross-references
Cell line collections ATCC; CRL-2083 - Discontinued
Other Wikidata; Q54799741
Entry history
Entry creation22-Sep-2015
Last entry update20-May-2021
Version number13