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Cellosaurus KM12-LX (CVCL_4M94)

[Text version]

Cell line name KM12-LX
Synonyms KM12LX
Accession CVCL_4M94
Resource Identification Initiative To cite this cell line use: KM12-LX (RRID:CVCL_4M94)
Sequence variations TPM3-NTRK1 gene fusion (from parent cell line).
Homozygous for ACVR2A p.Lys437fs*5 (c.1310delA) (from parent cell line).
Heterozygous for APC p.Asn1819fs*7 (c.5454_5455insA) (from parent cell line).
Heterozygous for BRCA2 p.Asn1784Hisfs*7 (c.5350_5351delAA) (from parent cell line).
Heterozygous for PTEN p.Gly129Ter (c.385G>T) and p.Lys267fs*9 (c.800delA) (from parent cell line).
Heterozygous for TGFBR2 p.Lys128Serfs*35 (c.383delA) (from parent cell line).
Heterozygous for TP53 p.Arg72fs*51 (c.215delG) (from parent cell line).
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9547 (KM12-C)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line

PubMed=1679016; DOI=10.1016/0014-4827(91)90451-Y
Matsushita Y., Nakamori S., Seftor E.A., Hendrix M.J.C., Irimura T.
Human colon carcinoma cells with increased invasive capacity obtained by selection for sialyl-dimeric LeX antigen.
Exp. Cell Res. 196:20-25(1991)

PubMed=7529188; DOI=10.1006/excr.1995.1027
Izumi Y., Taniuchi Y., Tsuji T., Smith C.W., Nakamori S., Fidler I.J., Irimura T.
Characterization of human colon carcinoma variant cells selected for sialyl Lex carbohydrate antigen: liver colonization and adhesion to vascular endothelial cells.
Exp. Cell Res. 216:215-221(1995)

Other Wikidata; Q54900060
Entry history
Entry creation22-Sep-2015
Last entry updated05-Jul-2019
Version number7