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Cellosaurus HMC-1 5C6 (CVCL_4T80)

[Text version]
Cell line name HMC-1 5C6
Synonyms HMC-1(5C6); HMC1-5C6; 5C6
Accession CVCL_4T80
Resource Identification Initiative To cite this cell line use: HMC-1 5C6 (RRID:CVCL_4T80)
Comments Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Mast cell; CL=CL_0000097.
Sequence variations
  • Mutation; HGNC; 6342; KIT; Simple; p.Val560Gly (c.1679T>G); ClinVar=VCV000375916; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6342; KIT; Simple; p.Asp816Val (c.2447A>T); ClinVar=VCV000013852; Zygosity=Heterozygous (from parent cell line).
Disease Mast cell leukemia (NCIt: C3169)
Mast cell leukemia (ORDO: Orphanet_98851)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0003 (HMC-1)
Sex of cell Male
Age at sampling 52Y
Category Cancer cell line
Publications

PubMed=8950460; DOI=10.1007/BF02505297
Weber S., Babina M., Kruger-Krasagakes S., Grutzkau A., Henz B.M.
A subclone (5C6) of the human mast cell line HMC-1 represents a more differentiated phenotype than the original cell line.
Arch. Dermatol. Res. 288:778-782(1996)

PubMed=22363102; DOI=10.1155/2012/274347
Walia D.S., Sharma M., Raveendran V.V., Zhou J.-P., Sharma R., Stechschulte D.J., Dileepan K.N.
Human mast cells (HMC-1 5C6) enhance interleukin-6 production by quiescent and lipopolysaccharide-stimulated human coronary artery endothelial cells.
Mediators Inflamm. 2012:274347.1-274347.10(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4T80
Encyclopedic resources Wikidata; Q54889907
Entry history
Entry creation22-Sep-2015
Last entry update05-Oct-2023
Version number11