ID   HMC-1 5C6
AC   CVCL_4T80
SY   HMC-1(5C6); HMC1-5C6; 5C6
DR   cancercelllines; CVCL_4T80
DR   Wikidata; Q54889907
RX   PubMed=8950460;
RX   PubMed=22363102;
CC   Sequence variation: Mutation; HGNC; 6342; KIT; Simple; p.Val560Gly (c.1679T>G); ClinVar=VCV000375916; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6342; KIT; Simple; p.Asp816Val (c.2447A>T); ClinVar=VCV000013852; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: Mast cell; CL=CL_0000097.
DI   NCIt; C3169; Mast cell leukemia
DI   ORDO; Orphanet_98851; Mast cell leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0003 ! HMC-1
SX   Male
AG   52Y
CA   Cancer cell line
DT   Created: 22-09-15; Last updated: 05-10-23; Version: 11
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RX   PubMed=8950460; DOI=10.1007/BF02505297;
RA   Weber S., Babina M., Kruger-Krasagakes S., Grutzkau A., Henz B.M.;
RT   "A subclone (5C6) of the human mast cell line HMC-1 represents a more
RT   differentiated phenotype than the original cell line.";
RL   Arch. Dermatol. Res. 288:778-782(1996).
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RX   PubMed=22363102; DOI=10.1155/2012/274347;
RA   Walia D.S., Sharma M., Raveendran V.V., Zhou J.-P., Sharma R.,
RA   Stechschulte D.J., Dileepan K.N.;
RT   "Human mast cells (HMC-1 5C6) enhance interleukin-6 production by
RT   quiescent and lipopolysaccharide-stimulated human coronary artery
RT   endothelial cells.";
RL   Mediators Inflamm. 2012:274347.1-274347.10(2012).
//