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Cellosaurus Sf900+ (CVCL_4U10)

[Text version]

Cell line name Sf900+
Synonyms expressSF+; express SF+; Express Sf+; Sf+
Accession CVCL_4U10
Resource Identification Initiative To cite this cell line use: Sf900+ (RRID:CVCL_4U10)
Comments Group: Insect cell line.
Group: Recombinant protein production insect cell line.
Group: Vaccine production cell line.
Biotechnology: Used for the production of the porcine circovirus type 2 (PCV2) vaccine CircoFLEX. Used to produce the PCV2 ORF2 capsid protein (PubMed=29133148).
Derived from sampling site: Ovary.
Species of origin Spodoptera frugiperda (Fall armyworm) (NCBI Taxonomy: 7108)
Hierarchy Parent: CVCL_0549 (Sf9)
Sex of cell Female
Age at sampling Pupal stage
Category Spontaneously immortalized cell line

Smith G.E., Foellmer H.G., Knell J., DeBartolomeis J., Voznesensky A.I.
Spodoptera frugiperda single cell suspension cell line in serum-free media, methods of producing and using.
Patent number US6103526, 15-Aug-2000

PubMed=18304705; DOI=10.1016/j.vaccine.2007.11.053
Fachinger V., Bischoff R., Jedidia S.B., Saalmuller A., Elbers K.
The effect of vaccination against porcine circovirus type 2 in pigs suffering from porcine respiratory disease complex.
Vaccine 26:1488-1499(2008)

PubMed=22265860; DOI=10.1016/j.vaccine.2012.01.016
Cox M.M.
Recombinant protein vaccines produced in insect cells.
Vaccine 30:1759-1766(2012)

PubMed=29133148; DOI=10.1016/j.pep.2017.11.002
Geisler C., Jarvis D.L.
Adventitious viruses in insect cell lines used for recombinant protein expression.
Protein Expr. Purif. 144:25-32(2017)

Cell line collections ATCC; CRL-12579 - Discontinued
Other Wikidata; Q54953005
Entry history
Entry creation22-Sep-2015
Last entry update20-May-2021
Version number7