ID   Sf900+
AC   CVCL_4U10
SY   expresSF+; expressSF+; express SF+; Express Sf+; Sf+
DR   Wikidata; Q54953005
RX   Patent=US6103526;
RX   PubMed=18304705;
RX   PubMed=22265860;
RX   PubMed=23848607;
RX   PubMed=29133148;
CC   Group: Insect cell line.
CC   Group: Patented cell line.
CC   Group: Recombinant protein production insect cell line.
CC   Group: Vaccine production cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12579.
CC   Biotechnology: Used for the production of the porcine circovirus type 2 (PCV2) vaccine CircoFLEX. Used to produce the PCV2 ORF2 capsid protein (PubMed=29133148).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
OX   NCBI_TaxID=7108; ! Spodoptera frugiperda (Fall armyworm)
HI   CVCL_0549 ! Sf9
SX   Female
AG   Pupal stage
CA   Spontaneously immortalized cell line
DT   Created: 22-09-15; Last updated: 29-06-23; Version: 11
//
RX   Patent=US6103526;
RA   Smith G.E., Foellmer H.G., Knell J., DeBartolomeis J.,
RA   Voznesensky A.I.;
RT   "Spodoptera frugiperda single cell suspension cell line in serum-free
RT   media, methods of producing and using.";
RL   Patent number US6103526, 15-Aug-2000.
//
RX   PubMed=18304705; DOI=10.1016/j.vaccine.2007.11.053;
RA   Fachinger V., Bischoff R., Ben Jedidia S., Saalmuller A., Elbers K.;
RT   "The effect of vaccination against porcine circovirus type 2 in pigs
RT   suffering from porcine respiratory disease complex.";
RL   Vaccine 26:1488-1499(2008).
//
RX   PubMed=22265860; DOI=10.1016/j.vaccine.2012.01.016;
RA   Cox M.M.J.;
RT   "Recombinant protein vaccines produced in insect cells.";
RL   Vaccine 30:1759-1766(2012).
//
RX   PubMed=23848607; DOI=10.1021/pr400329k;
RA   An Y.-M., Rininger J.A., Jarvis D.L., Jing X.-H., Ye Z.-P., Aumiller J.J.,
RA   Eichelberger M.C., Cipollo J.F.;
RT   "Comparative glycomics analysis of influenza Hemagglutinin (H5N1)
RT   produced in vaccine relevant cell platforms.";
RL   J. Proteome Res. 12:3707-3720(2013).
//
RX   PubMed=29133148; DOI=10.1016/j.pep.2017.11.002;
RA   Geisler C., Jarvis D.L.;
RT   "Adventitious viruses in insect cell lines used for recombinant
RT   protein expression.";
RL   Protein Expr. Purif. 144:25-32(2017).
//