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Cellosaurus HROG17 (CVCL_4U45)

[Text version]
Cell line name HROG17
Accession CVCL_4U45
Resource Identification Initiative To cite this cell line use: HROG17 (RRID:CVCL_4U45)
Comments From: Linnebacher M.; University of Rostock; Rostock; Germany.
Population: Caucasian.
Doubling time: 32-42 hours (CLS=300938).
Omics: Deep exome analysis.
Omics: HLA class I peptidome analysis by proteomics.
Omics: HLA class II peptidome analysis by proteomics.
Derived from site: In situ; Brain, left parieto-occipital lobe.
Sequence variations
  • Mutation; HGNC; 9588; PTEN; Simple; p.Arg130Ter (c.388C>T); ClinVar=VCV000007819; Zygosity=Unspecified (CLS=300938).
HLA typing Source: PubMed=33592498
Class I
HLA-AA*11:01,66:01
HLA-BB*14:02,40:02
HLA-CC*01:02,08:02
Class II
HLA-DPDPA1*01:03,02:01
DPB1*04:01,11:01
HLA-DQDQA1*01:01,05:05
DQB1*03:01,05:01
HLA-DRDRB1*01:02,12:01
DRB3*02:02
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C6JX (HROG17-CIITA)
Originate from same individual CVCL_B7FQ ! HROG17 T1 M1
Sex of cell Male
Age at sampling 70Y
Category Cancer cell line
Publications

PubMed=23951083; DOI=10.1371/journal.pone.0071070
Mullins C.S., Schneider B., Stockhammer F., Krohn M., Classen C.F., Linnebacher M.
Establishment and characterization of primary glioblastoma cell lines from fresh and frozen material: a detailed comparison.
PLoS ONE 8:E71070-E71070(2013)

PubMed=33592498; DOI=10.1074/mcp.RA120.002201
Forlani G., Michaux J., Pak H., Huber F., Lauret Marie-Joseph E., Ramia E., Stevenson B.J., Linnebacher M., Accolla R.S., Bassani-Sternberg M.
CIITA-transduced glioblastoma cells uncover a rich repertoire of clinically relevant tumor-associated HLA-II antigens.
Mol. Cell. Proteomics 20:100032.1-100032.21(2021)

Cross-references
Cell line collections (Providers) CLS; 300938
Cell line databases/resources cancercelllines; CVCL_4U45
Encyclopedic resources Wikidata; Q54895317
Proteomic databases PRIDE; PXD020079
Entry history
Entry creation22-Sep-2015
Last entry update05-Oct-2023
Version number14