| Cell line name |
V79-hCYP1A2 |
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| Synonyms |
V79-CYP1A2; V79MZh1A2; XEMhIA2-MZ#1; XEMh1A2-MZ*1; XEMhIA2-MZ |
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| Accession |
CVCL_4V39 |
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| Resource Identification Initiative |
To cite this cell line use: V79-hCYP1A2 (RRID:CVCL_4V39) |
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| Comments |
Transfected with: HGNC; 2596; CYP1A2.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553. |
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| Sequence variations |
- Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
- Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
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| Species of origin |
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
(NCBI Taxonomy: 10029) |
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| Hierarchy |
Parent: CVCL_4V36 (V79MZ)
Children:
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| Sex of cell |
Male |
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| Age at sampling |
Adult |
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| Category |
Spontaneously immortalized cell line |
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| Publications | PubMed=1446722; DOI=10.1016/0926-6917(92)90017-7
Wolfel C., Heinrich-Hirsch B., Schulz-Schalge T., Seidel A., Frank H., Ramp U., Wachter F., Wiebel F.J., Gonzalez F.J., Greim H., Doehmer J.
Genetically engineered V79 Chinese hamster cells for stable expression of human cytochrome P450IA2.
Eur. J. Pharmacol. 228:95-102(1992) PubMed=8293790; DOI=10.1016/0926-6917(93)90052-R
Schmalix W.A., Maser H., Kiefer F., Reen R., Wiebel F.J., Gonzalez F.J., Seidel A., Glatt H.-R., Greim H., Doehmer J.
Stable expression of human cytochrome P450 1A1 cDNA in V79 Chinese hamster cells and metabolic activation of benzo[a]pyrene.
Eur. J. Pharmacol. 248:251-261(1993) PubMed=31112310; DOI=10.1002/em.22309
Zhu N., Hu K.-Q., Li Z.-H., Chen Y.-T., Liu Y.-G.
Micronuclei formation by promutagens in metabolism-incompetent V79 cells interacting with activation-proficient cells in various experimental settings.
Environ. Mol. Mutagen. 61:224-234(2020) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q54992632
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| Entry history |
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| Entry creation | 14-Dec-2015 |
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| Last entry update | 29-Jun-2023 |
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| Version number | 9 |
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