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Cellosaurus MCF-7/RTx6 (CVCL_4V43)

[Text version]

Cell line name MCF-7/RTx6
Synonyms MCF-7 Rtx6; RTx6; RTX6; RTx-6; Rtx-6
Accession CVCL_4V43
Resource Identification Initiative To cite this cell line use: MCF-7/RTx6 (RRID:CVCL_4V43)
Comments Selected for resistance to: ChEBI; CHEBI:41774; Tamoxifen.
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line

PubMed=6574477; DOI=10.1073/pnas.80.11.3158
Faye J.-C., Jozan S., Redeuilh G., Baulieu E.-E., Bayard F.
Physicochemical and genetic evidence for specific antiestrogen binding sites.
Proc. Natl. Acad. Sci. U.S.A. 80:3158-3162(1983)

Other Wikidata; Q54904377
Entry history
Entry creation14-Dec-2015
Last entry update02-Jul-2020
Version number7