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Cellosaurus KCL22/SR (CVCL_4V46)

[Text version]

Cell line name KCL22/SR
Accession CVCL_4V46
Resource Identification Initiative To cite this cell line use: KCL22/SR (RRID:CVCL_4V46)
Comments Selected for resistance to: ChEBI; CHEBI:45783; Imatinib (Gleevec; STI571).
Derived from sampling site: Pleural effusion.
Sequence variations BCR-ABL1 gene fusion (from parent cell line).
TP53 p.Pro301fs (c.901delC) (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2091 (KCL-22)
Sex of cell Female
Age at sampling 32Y
Category Cancer cell line

PubMed=12743326; DOI=10.1634/stemcells.21-3-315
Ohmine K., Nagai T., Tarumoto T., Miyoshi T., Muroi K., Mano H., Komatsu N., Takaku F., Ozawa K.
Analysis of gene expression profiles in an imatinib-resistant cell line, KCL22/SR.
Stem Cells 21:315-321(2003)

Other Wikidata; Q54899694
Entry history
Entry creation14-Dec-2015
Last entry update12-Mar-2020
Version number5