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Cellosaurus BT474-5FU[r] (CVCL_4V65)

[Text version]

Cell line name BT474-5FU[r]
Accession CVCL_4V65
Resource Identification Initiative To cite this cell line use: BT474-5FU[r] (RRID:CVCL_4V65)
Comments Selected for resistance to: ChEBI; CHEBI:46345; 5-fluorouracil (5-FU).
Sequence variations Heterozygous for MAPK1 p.His61Gln (c.183C>G) (from parent cell line).
Heterozygous for PIK3CA p.Lys111Asn (c.333G>C) (ClinVar=VCV000376483) (from parent cell line).
Homozygous for TP53 p.Glu285Lys (c.853G>A) (ClinVar=VCV000420133) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0179 (BT-474)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Web pages http://www.chemoscreen.com/product/bt474-5fur-dna
Other Wikidata; Q54798492
Entry history
Entry creation14-Dec-2015
Last entry update02-Jul-2020
Version number7