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Cellosaurus MCF7-AFA[r] (CVCL_4V66)

[Text version]

Cell line name MCF7-AFA[r]
Accession CVCL_4V66
Resource Identification Initiative To cite this cell line use: MCF7-AFA[r] (RRID:CVCL_4V66)
Comments Selected for resistance to: ChEBI; CHEBI:61390; Afatinib (BIBW-2992).
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Web pages http://www.chemoscreen.com/product/mcf7-afar-dna
Other Wikidata; Q54904462
Entry history
Entry creation14-Dec-2015
Last entry update02-Jul-2020
Version number7