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Cellosaurus MDA231-DOX[r] (CVCL_4V67)

[Text version]

Cell line name MDA231-DOX[r]
Accession CVCL_4V67
Resource Identification Initiative To cite this cell line use: MDA231-DOX[r] (RRID:CVCL_4V67)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Selected for resistance to: ChEBI; CHEBI:28748; Doxorubicin (Adriablastin; Adriamycin).
Sequence variations Heterozygous for BRAF p.Gly464Val (c.1391G>T) (ClinVar=VCV000040364) (from parent cell line).
Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for KRAS p.Gly13Asp (c.38G>A) (ClinVar=VCV000012580) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Homozygous for TP53 p.Arg280Lys (c.839G>A) (ClinVar=VCV000376657) (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0062 (MDA-MB-231)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
Web pages http://www.chemoscreen.com/product/mda231-doxr-cells
Cross-references
Other Wikidata; Q54904664
Entry history
Entry creation14-Dec-2015
Last entry update02-Jul-2020
Version number9