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Cellosaurus LoVo/L-OHP (CVCL_4V75)

Cell line name LoVo/L-OHP
Accession CVCL_4V75
Resource Identification Initiative To cite this cell line use: LoVo/L-OHP (RRID:CVCL_4V75)
Comments Selected for resistance to: ChEBI; CHEBI:31941; Oxaliplatin (Elotaxin; L-OHP).
Sequence variations Homozygous for ACVR2A p.Lys437fs*5 (c.1310delA) (from parent cell line).
APC p.Arg1114Ter (c.3340C>T), p.Met1431fs*42 (c.4289delC) and p.Arg2816Gln (c.8447G>A) (from parent cell line).
KRAS p.Gly13Asp (c.38G>A) (from parent cell line).
SMAD2 p.Ala292Val (c.875C>T) (from parent cell line).
Homozygous for TGFBR2 p.Lys128Serfs*35 (c.383delA) (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Derived from metastatic site: Left supraclavicular lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0399 (LoVo)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line

Liu Z., Qiu M., Tang Q.-L., Liu M., Lang N., Bi F.
Establishment and biological characteristics of oxaliplatin-resistant human colon cancer cell lines.
Chin. J. Cancer 29:661-667(2010)

Other Wikidata; Q54902906