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Cellosaurus SW620-OX (CVCL_4V76)

Cell line name SW620-OX
Accession CVCL_4V76
Resource Identification Initiative To cite this cell line use: SW620-OX (RRID:CVCL_4V76)
Comments Selected for resistance to: ChEBI; CHEBI:31941; Oxaliplatin (Elotaxin; L-OHP).
Sequence variations Homozygous for APC p.Gln1338Ter (c.4012C>T) (from parent cell line).
Homozygous for KRAS p.Gly12Val (c.35G>T) (from parent cell line).
Heterozygous for TP53 p.Arg273His (c.818G>A) and p.Pro309Ser (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0547 (SW620)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line

PubMed=24761924; DOI=10.7314/APJCP.2014.15.6.2911
Chian S., Li Y.-Y., Wang X.-J., Tang X.-W.
Luteolin sensitizes two oxaliplatin-resistant colorectal cancer cell lines to chemotherapeutic drugs via inhibition of the Nrf2 pathway.
Asian Pac. J. Cancer Prev. 15:2911-2916(2014)

Other Wikidata; Q54971187