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Cellosaurus SW620/L-OHP (CVCL_4V77)

[Text version]
Cell line name SW620/L-OHP
Accession CVCL_4V77
Resource Identification Initiative To cite this cell line use: SW620/L-OHP (RRID:CVCL_4V77)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:31941; Oxaliplatin (Elotaxin; L-OHP).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0547 (SW620)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=20591218
Liu Z., Qiu M., Tang Q.-L., Liu M., Lang N., Bi F.
Establishment and biological characteristics of oxaliplatin-resistant human colon cancer cell lines.
Chin. J. Cancer 29:661-667(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4V77
Encyclopedic resources Wikidata; Q54971189
Entry history
Entry creation14-Dec-2015
Last entry update05-Oct-2023
Version number15