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Cellosaurus K562/AS-3 (CVCL_4V84)

[Text version]

Cell line name K562/AS-3
Accession CVCL_4V84
Resource Identification Initiative To cite this cell line use: K562/AS-3 (RRID:CVCL_4V84)
Comments Selected for resistance to: ChEBI; CHEBI:30621; Diarsenic trioxide (ATO; As2O3).
Derived from sampling site: Pleural effusion.
Sequence variations BCR-ABL1 gene fusion (from parent cell line).
Homozygous for TP53 p.Gln136fs*13 (c.406_407insC) (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line

PubMed=17261498; DOI=10.1532/IJH97.05142
Seo T., Urasaki Y., Ueda T.
Establishment of an arsenic trioxide-resistant human leukemia cell line that shows multidrug resistance.
Int. J. Hematol. 85:26-31(2007)

Other Wikidata; Q54899405
Entry history
Entry creation14-Dec-2015
Last entry update12-Mar-2020
Version number8