Cellosaurus SKOV-3TR (CVCL_4V89)

Cell line name SKOV-3TR
Accession CVCL_4V89
Resource Identification Initiative To cite this cell line use: SKOV-3TR (RRID:CVCL_4V89)
Comments Selected for resistance to: ChEBI; CHEBI:45863; Paclitaxel (Taxol).
Sequence variation: Heterozygous for APC p.Thr1556fs*9 (from parent cell line).
Sequence variation: Heterozygous for PIK3CA p.His1047Arg (from parent cell line).
Sequence variation: Homozygous for TP53 p.Ser90fs*33 (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=10095106; DOI=10.1016/S0378-1119(99)00042-6
Duan Z., Feller A.J., Toh H.C., Makastorsis T., Seiden M.V.
TRAG-3, a novel gene, isolated from a taxol-resistant ovarian carcinoma cell line.
Gene 229:75-81(1999)