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Cellosaurus SKOV-3TR (CVCL_4V89)

Cell line name SKOV-3TR
Accession CVCL_4V89
Resource Identification Initiative To cite this cell line use: SKOV-3TR (RRID:CVCL_4V89)
Comments Selected for resistance to: ChEBI; CHEBI:45863; Paclitaxel (Taxol).
Sequence variations Heterozygous for APC p.Thr1556fs*9 (c.4666delA) (from parent cell line).
Heterozygous for PIK3CA p.His1047Arg (c.3140A>G) (from parent cell line).
Homozygous for TP53 p.Ser90fs*33 (c.267delC) (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line

PubMed=10095106; DOI=10.1016/S0378-1119(99)00042-6
Duan Z., Feller A.J., Toh H.C., Makastorsis T., Seiden M.V.
TRAG-3, a novel gene, isolated from a taxol-resistant ovarian carcinoma cell line.
Gene 229:75-81(1999)

Other Wikidata; Q54954765