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Cellosaurus SK-OV-3/CMV-Luc (CVCL_4Y19)

[Text version]

Cell line name SK-OV-3/CMV-Luc
Accession CVCL_4Y19
Resource Identification Initiative To cite this cell line use: SK-OV-3/CMV-Luc (RRID:CVCL_4Y19)
Comments Characteristics: Expression of luciferase is under the control of the CMV promoter.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Sequence variations Mutation; HGNC; 583; APC; Simple; p.Thr1556Leufs*9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Ser90Profs*33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): JCRB

Markers:
AmelogeninX
CSF1PO11
D5S81811
D7S82013,14
D13S3178,11
D16S53912
TH019,9.3
TPOX8,11
vWA17,18

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Cross-references
Cell line collections JCRB; JCRB1594
JCRB; NIHS0736 - Discontinued
Other Wikidata; Q54954502
Entry history
Entry creation14-Dec-2015
Last entry update20-May-2021
Version number12