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Cellosaurus PC-3 D12 (CVCL_4Y40)

[Text version]
Cell line name PC-3 D12
Accession CVCL_4Y40
Resource Identification Initiative To cite this cell line use: PC-3 D12 (RRID:CVCL_4Y40)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:4672; Docetaxel anhydrous (Taxotere).
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=21982118; DOI=10.1186/1476-4598-10-126
O'Neill A.J., Prencipe M., Dowling C., Fan Y., Mulrane L., Gallagher W.M., O'Connor D., O'Connor R., Devery A.M., Corcoran C., Rani S., O'Driscoll L., Fitzpatrick J.M., Watson R.W.G.
Characterisation and manipulation of docetaxel resistant prostate cancer cell lines.
Mol. Cancer 10:126.1-126.13(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_4Y40
Encyclopedic resources Wikidata; Q54938406
Entry history
Entry creation14-Dec-2015
Last entry update05-Oct-2023
Version number11