Home  |  Contact

Cellosaurus PC-3 D12 (CVCL_4Y40)

[Text version]

Cell line name PC-3 D12
Accession CVCL_4Y40
Resource Identification Initiative To cite this cell line use: PC-3 D12 (RRID:CVCL_4Y40)
Comments Selected for resistance to: ChEBI; CHEBI:4672; Docetaxel anhydrous (Taxotere).
Sequence variations Homozygous for TP53 p.Lys139fs*31 (c.413delC) (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Derived from metastatic site: Bone.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=21982118; DOI=10.1186/1476-4598-10-126
O'Neill A.J., Prencipe M., Dowling C., Fan Y., Mulrane L., Gallagher W.M., O'Connor D., O'Connor R., Devery A., Corcoran C., Rani S., O'Driscoll L., Fitzpatrick J.M., Watson R.W.
Characterisation and manipulation of docetaxel resistant prostate cancer cell lines.
Mol. Cancer 10:126-126(2011)

Cross-references
Other Wikidata; Q54938406